Virtual Screening (VS) is a core in-silico technology in medicinal and computational chemistry. Several tools have been developed to exploit protein structures or collections of compounds to provide a quick and economical method for the discovery of novel active compounds. Hence, the comparative evaluation of VS algorithms becomes a fundamental exercise to assess the applicability […]
Researchers at Bellvitge Biomedical Research Institute will develop a research project with the company Pharmacelera to look for new molecules that block the cohesin complex, with applications in several difficult-to-treat cancers, such as myeloid leukemia, glioblastomas, Ewing sarcomas, colon cancer and bladder cancer. The cell cycle research group of the Bellvitge Biomedical Research Institute (IDIBELL), […]
PharmScreen evolves day by day thanks to the feedback of many computational and medicinal chemists! We have been incorporating different features to our 3D virtual screening tool. Have a look to the latest updates! Major updates Field visualization: Now you are able to visualize the different molecular fields of your reference compound as well as […]
Why protein-protein interactions are important? Protein-protein interactions (PPI) play a major role in several of the cellular functions and processes that take place in our organism. Researchers estimate that around 130.000 binary interactions occur between different proteins (1). These interactions also regulate several of the pathogenic mechanisms that bacteria use during the infection process. The […]